Interfacing peripheral nerve with macro-sieve electrodes following spinal cord injury

Macro-sieve electrodes were implanted in the sciatic nerve of five adult male Lewis rats following spinal cord injury to assess the ability of the macro-sieve electrode to interface regenerated peripheral nerve fibers post-spinal cord injury. Each spinal cord injury was performed via right lateral hemisection of the cord at the T9–10 site. Five months post-implantation, the ability of the macro-sieve electrode to interface the regenerated nerve was assessed by stimulating through the macro-sieve electrode and recording both electromyography signals and evoked muscle force from distal musculature. Electromyography measurements were recorded from the tibialis anterior and gastrocnemius muscles, while evoked muscle force measurements were recorded from the tibialis anterior, extensor digitorum longus, and gastrocnemius muscles. The macro-sieve electrode and regenerated sciatic nerve were then explanted for histological evaluation. Successful sciatic nerve regeneration across the macro-sieve electrode interface following spinal cord injury was seen in all five animals. Recorded electromyography signals and muscle force recordings obtained through macro-sieve electrode stimulation confirm the ability of the macro-sieve electrode to successfully recruit distal musculature in this injury model. Taken together, these results demonstrate the macro-sieve electrode as a viable interface for peripheral nerve stimulation in the context of spinal cord injury

Two Populations of Young Massive Star Clusters in Arp 220

We present new optical observations of young massive star clusters in Arp 220, the nearest ultraluminous infrared galaxy, taken in UBVI with the Hubble Space Telescope ACS/HRC camera. We find a total of 206 probable clusters whose spatial distribution is centrally concentrated toward the nucleus of Arp 220. We use model star cluster tracks to determine ages, luminosities, and masses for 14 clusters with complete UBVI indices or previously published near-infrared data. We estimate rough masses for 24 additional clusters with I < 24 mag from BVI indices alone. The clusters with useful ages fall into two distinct groups: a ``young'' population (< 10 Myr) and an intermediate-age population (~300 Myr). There are many clusters with masses clearly above 10^6 Msun and possibly even above 10^7 Msun in the most extreme instances. These masses are high enough that the clusters being formed in the Arp 220 starburst can be considered as genuine young globular clusters. In addition, this study allows us to extend the observed correlation between global star formation rate and maximum cluster luminosity by more than an order of magnitude in star formation rate.Comment: 30 pages, 8 figures; figs 1-3 in color; accepted to Ap

Deterministic creation, pinning, and manipulation of quantized vortices in a Bose-Einstein condensate

We experimentally and numerically demonstrate deterministic creation and manipulation of a pair of oppositely charged singly quantized vortices in a highly oblate Bose-Einstein condensate (BEC). Two identical blue-detuned, focused Gaussian laser beams that pierce the BEC serve as repulsive obstacles for the superfluid atomic gas; by controlling the positions of the beams within the plane of the BEC, superfluid flow is deterministically established around each beam such that two vortices of opposite circulation are generated by the motion of the beams, with each vortex pinned to the \emph{in situ} position of a laser beam. We study the vortex creation process, and show that the vortices can be moved about within the BEC by translating the positions of the laser beams. This technique can serve as a building block in future experimental techniques to create, on-demand, deterministic arrangements of few or many vortices within a BEC for precise studies of vortex dynamics and vortex interactions.Comment: 9 pages, 7 figure

Investigation of the role of selenium in the nutrition and physiology of neural tissues of chickens and turkeys

Endogenous selenium concentrations in selected tissue of chickens, turkeys, and coturni

First-order melting of a weak spin-orbit Mott insulator into a correlated metal

The electronic phase diagram of the weak spin-orbit Mott insulator (Sr(1-x)Lax)3Ir2O7 is determined via an exhaustive experimental study. Upon doping electrons via La substitution, an immediate collapse in resistivity occurs along with a narrow regime of nanoscale phase separation comprised of antiferromagnetic, insulating regions and paramagnetic, metallic puddles persisting until x~0.04. Continued electron doping results in an abrupt, first-order phase boundary where the Neel state is suppressed and a homogenous, correlated, metallic state appears with an enhanced spin susceptibility and local moments. As the metallic state is stabilized, a weak structural distortion develops and suggests a competing instability with the parent spin-orbit Mott state.Comment: 5 pages, 4 figure

Phenomenological theory of spin excitations in La- and Y-based cuprates

Motivated by recent inelastic neutron scattering (INS) experiments on La-based cuprates and based on the fermiology theories, we study the spin susceptibility for La-based (e.g., La$_{2-x}$Sr$_x$CuO$_4$) and Y-based (e.g., YBa$_2$Cu$_3$O$_y$) cuprates, respectively. The spin excitation in YBa$_2$Cu$_3$O$_y$ is dominated by a sharp resonance peak at the frequency 40 meV in the superconducting state. Below and above the resonance frequency, the incommensurate (IC) peaks develop and the intensity of the peaks decreases dramatically. In the normal state, the resonant excitation does not occur and the IC peaks are merged into commensurate ones. The spin excitation of La$_{2-x}$Sr$_x$CuO$_4$ is significantly different from that of Y-based ones, namely, the resonance peak does not exist due to the decreasing of the superconducting gap and the presence of the possible spin-stripe order. The spectra are only enhanced at the expected resonance frequency (about 18 meV) while it is still incommensurate. On the other hand, another frequency scale at the frequency 55 meV is also revealed, namely the spectra are commensurate and local maximum at this frequency. We elaborate all the results based on the Fermi surface topology and the d-wave superconductivity, and suggest that the spin-stripe order be also important in determining the spin excitation of La-based cuprates. A coherent picture for the spin excitations is presented for Y-based and La-based cuprates.Comment: 8 pages, 8 figure

Renormalization Group Treatment of Nonrenormalizable Interactions

The structure of the UV divergencies in higher dimensional nonrenormalizable theories is analysed. Based on renormalization operation and renormalization group theory it is shown that even in this case the leading divergencies (asymptotics) are governed by the one-loop diagrams the number of which, however, is infinite. Explicit expression for the one-loop counter term in an arbitrary D-dimensional quantum field theory without derivatives is suggested. This allows one to sum up the leading asymptotics which are independent of the arbitrariness in subtraction of higher order operators. Diagrammatic calculations in a number of scalar models in higher loops are performed to be in agreement with the above statements. These results do not support the idea of the na\"ive power-law running of couplings in nonrenormalizable theories and fail (with one exception) to reveal any simple closed formula for the leading terms.Comment: LaTex, 11 page